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Advances in technology have made surgeries to remove those growths much more common.

Zeitels estimates he's performed about 75,000 voice operations, 500-700 of those on singers -- including Adele, The Who's lead singer Roger Daltrey, and Aerosmith's Steven Tyler. Most of the singers he has performed on have been opera singers, because of the substantial demands on their voice.

"You can't do marathons to train for marathons," Zeitels said. "There is a simple amount of mileage that vocal tissues can handle."

Zeitels has been developing a special gel that he hopes will allow singers to restore and preserve their voices.

When Zeitels explained the idea of the biogel to Julie Andrews during dinner one night, he mentioned that one of his reservations was that he didn't know how long it would work.

"Well, for people like me, even if it would last for a while we could utilize that and get things done," he remembers Andrews saying. "So, we came to think that the way to go at it was not to go for a home run, the perfect fix, but to get it to first base."

Now, he says the gel is ready for human trial.

"The holy grail is to inject a biogel into the vocal cord and restore it. So from a performing perspective, these folks who so-called can't sing anymore are totally fit to sing. Julie Andrews could sing beautifully tomorrow if she had the biogel. It's not that she's too old to sing."

Both Andrews, who went to Zeitels after losing pliability in her vocal cords due to a poor surgery, and Tyler encouraged Zeitels and MIT scientist Bob Langer to go forward with the biogel project, even contributing money to the development.

"It's not some magic potion," Zeitels said. "We're just making the vocal cords pure."

The gel is currently in a primitive form, but Zeitels is confident it will work in humans; trials will tell the degree to which the current form will work.